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SJHH / Coronavirus/ St. Joseph’s Healthcare Hamilton Monoclonal Antibody Clinic

St. Joseph’s Healthcare Hamilton Monoclonal Antibody Clinic

St. Joseph’s Healthcare Hamilton, in association with local and regional partners, is providing patients with the ability to access Monoclonal Antibodies for the early treatment of COVID-19.

The pilot program provides treatment for outpatients with COVID-19, who are at high-risk of progression to severe illness. While the first line of defense against COVID-19 is vaccination, this treatment will help to address the growing number of hospitalizations in high-risk individuals.

A monoclonal antibody is a type of protein that attaches to the spike protein of the COVID-19 virus and prevents the virus from entering and infecting healthy cells within the body. This therapy may help reduce the risk of progressing from mild or moderate COVID-19 to severe infection that requires hospitalization for high-risk individuals.

Initial studies show that COVID-19 monoclonal antibody therapy reduces hospitalization by 71% and reduces death by 70% in high-risk COVID-positive patients.

The Monoclonal Antibody Therapy Clinic is located at St. Joseph’s Healthcare Hamilton’s Charlton Campus (50 Charlton Ave. E.).


Am I eligible for monoclonal antibody therapy?

High-risk individuals, unvaccinated, immunocompromised or those who have underlying medical conditions may be eligible.
Please speak to a health care provider to assess your eligibility.

Are these a replacement for vaccination?

No, vaccination is still very important, and has greater effects than monoclonal therapy can offer.

Can it be administered within a community setting for those who are incapable of travelling to the hospital?

At this time, the therapy can only be administered in the outpatient clinic at SJHH.

What should I expect?

On the day of your infusion, you’ll meet with your physician and nursing team to answer questions, and you’ll get your vital signs checked. If you agree to the infusion, you’ll have an intravenous placed. You’ll get a 30–60-minute infusion of the medication and be monitored for another 60 minutes afterwards. After this, you’ll go home and continue your isolation from your local public health unit. There are no further doses needed.

There are very few side effects described, and many of them are since patients have COVID-19.  Patient are monitored for allergic reactions which are rare. 

What are the next steps for patients after treatment?

Patients are still considered contagious and must continue to follow all public health guidelines, which include mandatory isolation periods. They are permitted to leave isolation for medical treatments.

How do I get a referral?

Patients will be referred to the clinic by St. Joseph’s Healthcare Hamilton & Hamilton Health Sciences testing & assessment clinic, or their health provider. For more information contact: 905-522-1155 x 34012.

We highly recommend patients discuss the referral with their healthcare provider. Given the current situation self-referrals will be accepted in very limited circumstances.

I am a physician. How do I refer my patient to the MAB Clinic?

You can download the referral form here or contact us at 905-522-1155 x 34012.

While we strive to get everyone who is referred access, there may be circumstances where we cannot offer treatment due to clinic demands.