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SJHH / Coronavirus/ St. Joseph’s Healthcare Hamilton Monoclonal Antibody Clinic

St. Joseph’s Healthcare Hamilton Monoclonal Antibody Clinic

St. Joseph’s Healthcare Hamilton, in association with local and regional partners, is providing patients with the ability to access Monoclonal Antibodies for the early treatment of COVID-19.

The pilot program provides treatment for outpatients with COVID-19, who are at high-risk of progression to severe illness. While the first line of defense against COVID-19 is vaccination, this treatment will help to address the growing number of hospitalizations in high-risk individuals.

A monoclonal antibody is a type of protein that attaches to the spike protein of the COVID-19 virus and prevents the virus from entering and infecting healthy cells within the body. This therapy may help reduce the risk of progressing from mild or moderate COVID-19 to severe infection that requires hospitalization for high-risk individuals.

Initial studies show that COVID-19 monoclonal antibody therapy reduces hospitalization by 71% and reduces death by 70% in high-risk COVID-positive patients.

The Monoclonal Antibody Therapy Clinic is located at St. Joseph’s Healthcare Hamilton’s Charlton Campus (50 Charlton Ave. E.).


Am I eligible for monoclonal antibody therapy?

Patients who test positive for COVID-19 and have symptoms lasting 7 days or less are eligible if they meet the criteria below. Patients need to be able to get to St. Joseph’s Healthcare Hamilton while following public health guidelines, by driving directly to the hospital and driving directly home.

Unvaccinated individuals – those over the age of 50 OR those under the age of 50 with the following risk factors: Chronic heart disease (Including hypertension), Chronic Lung disease (including asthma), Obesity, Metabolic disease (including diabetes), Chronic Kidney Disease, Chronic Liver disease, have cancer or other immune supressing conditions/medications, or are pregnant.

Vaccinated individuals – those who have cancer on active chemotherapy, bone marrow transplants, kidney transplants, or are on certain immune supressing medications.

Are these a replacement for vaccination?

No, vaccination is still very important, and has greater effects than monoclonal therapy can offer.

Can it be administered within a community setting for those who are incapable of travelling to the hospital?

At this time, the therapy can only be administered in the outpatient clinic at SJHH.

What should I expect?

On the day of your infusion, you’ll meet with your physician and nursing team to answer questions, and you’ll get your vital signs checked. If you agree to the infusion, you’ll have an intravenous placed. You’ll get a 30–60-minute infusion of the medication and be monitored for another 60 minutes afterwards. After this, you’ll go home and continue your isolation from your local public health unit. There are no further doses needed.

There are very few side effects described, and many of them are since patients have COVID-19.  Patient are monitored for allergic reactions which are rare. 

What are the next steps for patients after treatment?

Patients are still considered contagious and must continue to follow all public health guidelines, which include isolation for ten days. They are permitted to leave isolation for medical treatments.

How do I get a referral?

Patients will be referred to the clinic by St. Joseph’s Healthcare Hamilton & Hamilton Health Sciences testing & assessment clinic, or their health provider. For more information contact: 905-522-1155 x 34012.

I am a physician. How do I refer my patient to the MAB Clinic?

You can download the referral form here or contact us at 905-522-1155 x34012.